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Harvard stem cell scientists have successfully converted skins cells from patients with early-onset Alzheimer's into the types of neurons that are affected by the disease, making it possible for the first time to study this leading form of dementia in living human cells. This may also make it possible to develop therapies far more quickly and accurately than before.

Research from Karolinska Institutet in Sweden suggests that the expression of the so called MYC gene is important and necessary for neurogenesis in the spinal cord. The findings are being published in the journal EMBO Reports.

International Stem Cell Corporation, a California-based biotechnology company developing novel stem cell-based therapies and biomedical products, today announced positive data from the first interim analysis of the ongoing IND-enabling pharmacology/toxicology primate study being conducted under the supervision of Professor D. Eugene Redmond Jr. MD, of Yale University Medical School.

In a study that began in a pair of infant siblings with a rare heart defect, Johns Hopkins researchers say they have identified a key molecular switch that regulates heart cell division and normally turns the process off around the time of birth. Their research, they report, could advance efforts to turn the process back on and regenerate heart tissue damaged by heart attacks or disease.

In space, things don't always behave the way we expect them to. In the case of cancer, researchers have found that this is a good thing: some tumors seem to be much less aggressive in the microgravity environment of space compared to their behavior on Earth.

Researchers in London, UK, are investigating the effectiveness of stem cell therapies for facial reconstruction.A joint team, from London's Great Ormond Street Hospital for Children and University College London's Institute of Child Health, has published the findings of their research in the journal Nanomedicine.

A new study led by Weill Cornell Medical College scientists shows that the most common genetic form of mental retardation and autism occurs because of a mechanism that shuts off the gene associated with the disease.

Adult stem cells and cancer cells have many things in common, including an ability to migrate through tiny gaps in tissue. Both types of cells also experience a trade-off when it comes to this ability; having a flexible nucleus makes migration easier but is worse at protecting the nucleus' DNA compared to a stiffer nucleus.

UT Southwestern Medical Center researchers created new nerve cells in the brains and spinal cords of living mammals without the need for stem cell transplants to replenish lost cells.

Our cells don't live in a vacuum. They are surrounded by a complex, nurturing matrix that is essential for many biological functions, including growth and healing.In all multicellular organisms, including people, cells make their own extracellular matrix. But in the lab, scientists attempting to grow tissue must provide a scaffold for cells to latch onto as they grow and proliferate.

Team finds that some cells activate only one of their two gene copies during development, altering protein yields and raising new questionsWe are a product of our parents. Maybe you have your mother's large, dark eyes, and you inherited your father's infectious smile.

Pleural mesothelioma, is an aggressive form of lung cancer strongly linked to asbestos exposure, which has very limited treatment options and is associated with poor patient survival, with most having less than a year left to live once diagnosed.

A study co-published in Nature Medicine by University of Toronto researcher Penney Gilbert has determined a stem cell based method for restoring strength to damaged skeletal muscles of the elderly.Skeletal muscles are some of the most important muscles in the body, supporting functions such as sitting, standing, blinking and swallowing.

In the battle against infection, immune cells are the body's offense and defense - some cells go on the attack while others block invading pathogens. It has long been known that a population of blood stem cells that resides in the bone marrow generates all of these immune cells.

There have been several reports in recent years of scientists reprogramming skin cells so they transform into cells that are similar to cells from other organs, such as the heart, the pancreas and even brain cells.

Researchers in Bern have discovered that, during a viral infection, immune cells control the blood stem cells in the bone marrow and therefore also the body's own defences. The findings could allow for new forms of therapy, such as for bone marrow diseases like leukaemia.

A new study released in Stem Cells Translational Medicine shows that many patients with defects to the skull, face or jaw bone might benefit from reconstructive surgery combining stem cells taken from adipose (fat) tissue seeded on resorbable scaffolds.These defects can be due to congenital malformations, such as cleft lip and palate, or to traumatic injuries or surgery to remove a tumor.

The power of regenerative medicine appears to have turned science fiction into scientific reality - by allowing scientists to transform skin cells into cells that closely resemble beating heart cells. However, the methods required are complex, and the transformation is often incomplete.

The largest ever trial of adult stem cell therapy in heart attack patients has begun at The London Chest Hospital in the UK. Heart disease is the world's leading cause of death. Globally, more than 17 million people died from heart disease last year. In the US, over 1 million people suffer a heart attack each year, and about half of them die.

Parcell Laboratories, developer of novel therapeutics based on its patented adult stem cell platform technology, the ELA® cell, is partnering with the University of Pittsburgh Medical Center (UPMC) to study a new stem cell-based wrinkle reduction treatment.